Publications

A selection of our common publications on the topic of placebo/nocebo effects:

Petrie KJ, Rief W.
Psychobiological Mechanisms of Placebo and Nocebo Effects: Pathways to Improve Treatments and Reduce Side Effects.
Annu Rev Psychol. 2019;70:599-625.

Zunhammer M, Bingel U, Wager TD; Placebo Imaging Consortium.
Placebo Effects on the Neurologic Pain Signature: A Meta-analysis of Individual Participant Functional Magnetic Resonance Imaging Data.
JAMA Neurol. 2018;75:1321-1330.

Evers AWM, Colloca L, Blease C, Annoni M, Atlas LY, Benedetti F, Bingel U, Büchel C, Carvalho C, Colagiuri B, Crum AJ, Enck P, Gaab J, Geers AL, Howick J, Jensen KB, Kirsch I, Meissner K, Napadow V, Peerdeman KJ, Raz A, Rief W, Vase L, Wager TD, Wampold BE, Weimer K, Wiech K, Kaptchuk TJ, Klinger R, Kelley JM.
Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus.
Psychother Psychosom. 2018;87:204-210.

Kube T, Glombiewski JA, Rief W.
Using Different Expectation Mechanisms to Optimize Treatment of Patients With Medical Conditions: A Systematic Review.
Psychosom Med. 2018;80:535-543.

Kirchhof J, Petrakova L, Brinkhoff A, Benson S, Schmidt J, Unteroberdörster M, Wilde B, Kaptchuk TJ, Witzke O, Schedlowski M.
Learned immunosuppressive placebo responses in renal transplant patients.
Proc Natl Acad Sci. 2018; 115:4223-4227.

Salzmann S, Euteneuer F, Laferton JAC, Auer CJ, Shedden-Mora MC, Schedlowski M, Moosdorf R, Rief W.
Effects of Preoperative Psychological Interventions on Catecholamine and Cortisol Levels After Surgery in Coronary Artery Bypass Graft Patients: The Randomized Controlled PSY-HEART Trial.
Psychosom Med. 2017;79:806-814.

Zunhammer M, Ploner M, Engelbrecht C, Bock J, Kessner SS, Bingel U.
The effects of treatment failure generalize across different routes of drug administration.
Sci Transl Med. 2017;9(393).

Rief W, Shedden-Mora MC, Laferton JA, Auer C, Petrie KJ, Salzmann S, Schedlowski M, Moosdorf R.
Preoperative optimization of patient expectations improves long-term outcome in heart surgery patients: results of the randomized controlled PSY-HEART trial.
BMC Med. 2017;15:4.

Roderigo T, Benson S, Schöls M, Hetkamp M, Schedlowski M, Enck P, Elsenbruch S.
Effects of acute psychological stress on placebo and nocebo responses in a clinically relevant model of viseroception
Pain. 2017;1489-1498

Zunhammer M, Ploner M, Engelbrecht C, Bock J, Kessner S, Bingel U.
The effects of treatment failure generalize across different routes of drug administration
Sci Transl Med. 2017;9:393.

Enck P, Chae Y, Elsenbruch S.
Novel designs and paradigms to study the placebo responce in gastroenterology
Curr Opin Pharmacol. 2017;72-79

Nestoriuc Y, von Blanckenburg P, Schuricht F, Barsky AJ, Hadji P, Albert US, Rief W.
Is it best to expect the worst? Influence of patients' side-effect expectations on endocrine treatment outcome in a 2-year prospective clinical cohort study.
Ann Oncol. 2016;27:1909-15.

Rief W
, Barsky AJ, Bingel U, Doering BK, Schwarting R, Wöhr M, Schweiger U.
Rethinking psychopharmacotherapy: The role of treatment context and brain plasticity in antidepressant and antipsychotic interventions.
Neurosci Biobehav Rev. 2016;60:51-64.

Nestoriuc Y, von Blanckenburg P, Schuricht F, Barsky AJ, Hadji P, Albert US, Rief W.
Is it best to expect the worst? Influence of patients' side-effect expectations on endocrine treatment outcome in a 2-year prospective clinical cohort study.
Ann Oncol. 2016;1909-15.

Elsenbruch S, Enck P.
Placebo effects and their determinants in gastrointestinal disorders.
Nat Rev Gastroenterol Hepatol 2015;472-85.

Schedlowski M, Enck P, Rief W, Bingel U.
Neuro-Bio-Behavioral Mechanisms of Placebo nd Nocebo Responses: Implications for Clinical Trials and Clinical Practice.
Pharmacol Rev, 2015;697-730.

Rief W
, Glombiewski JA, Gollwitzer M, Schubö A, Schwarting R, Thorwart A.
Expectancies as core features of mental disorders.
Curr Opin Psychiatry, 2015.

Wendt L, Albring A, Benson S, Engler H, Engler A, Hinney A, Rief W, Witzke O, Schedlowski M.
Catechol-O-methyltransferase Val158Met polymorphism is associated with somatosensory amplification and nocebo responses.
PLoS One 15, 2014.

Albring A, Wendt L, Benson S, Nissen S, Yavuz Z, Engler H, Witzke O, Schedlowski M.
Preserving learned immunosuppressive placebo response: perspectives for clinical application.
Clinical Pharmacology & Therapeutics 2014;247-255.

Bingel U; For the Placebo Competence Team.
Avoiding Nocebo Effects to Optimize Treatment Outcome.
JAMA 2014.

Enck P, Bingel U, Schedlowski M, Rief W.

The placebo response in medicine: minimize, maximize or personalize.
Nature Review Drug Discovery 2013;191-204.

Vits S, Cesko E, Benson S, Rueckert A, Hillen U, Schadendorf D, Schedlowski M.
Cognitive factors mediate placebo responses in patients with house dust mite allergy.
PloS One 18, 2013.

Glombiewski JA, Nestoriuc Y, Rief W, Glaesmer H & Braehler E.
Medication adherence in the general population.
PLoS One 7, 2013.

Doering BK, Rief W.
Utilizing placebo mechanisms for dose reduction in pharmacotherapy
Trends Pharmacol Sci 2012;165-72.

Ober K, Benson S, Vogelsang M, Bylica A, Günther D, Witzke O, Kribben A, Engler H, Schedlowski M.
Plasma Noradrenaline and State Anxiety Levels Predict Placebo Response in Learned Immunosuppression.
Clinical Pharmacology & Therapeutics 2012;220-26.

Rief W, Bingel U, Schedlowski M, Enck P.
Mechanisms involved in placebo and nocebo responses and implications for drug trials.
Clinical Pharmacology & Therapeutics 2011;722-26.

Rief W, Barsky AJ, Glombiewski JA, Nestoriuc Y, Glaesmer H & Brähler E.
Assessing general side effects in clinical trials: Reference data from the general population.
Pharmacoepidemiology & Drug Safety 2011;405-415.

Shedden Mora MC, Nestoriuc Y & Rief W.
Lessions learned from placebo groups in antidepressant trials.
Philosophical Transactions of the Royal Society B (Biological Sciences) 2011;1879-1888.

Bingel U, Wanigasekera V, Wiech K, Ni Mhuircheartaigh R, Lee MC, Ploner M, et al.
The effect of treatment expectation on drug efficacy: Imaging the analgesic benefit of the opioid remifentanil.
Science Translational Medicine 2011;70ra 14.

Bingel U, Colloca L, & Vase L.
Mechanisms and clinical implications of the placebo effect: Is there a potential for the elderly? A mini-review.
Gerontology 2010;354-63.

Eippert F, Finsterbusch J, Bingel U, Buchel C.
Direct evidence for spinal cord involvement in placebo analgesia.
Science 2009;404.

Bingel U, Tracey I.
Imaging CNS modulation of pain in humans.
Physiology 2008;371-80.